The TMOD1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to TMOD1, and Tropomodulin 1. This antibody recognizes Human, Mouse, and Rat antigen. The TMOD1 Antibody has been validated for the following applications: Immunohistochemistry, and Western Blot.
Description
Function: Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus.
Subunit Structure: Binds to the N-terminus of isoforms 2/3 of TPM3 and to actin.
Similarity: Belongs to the tropomodulin family